| P2x and P2y Purinergic receptor antagonist. Also shown to be an anti-parasitic and anti-tumor agent. Inhibits angiogenesis. | |
| Reference Price: | $125.00 Click to Order |
| More Information: | CAS [129-46-4] - 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid.hexasodium. - C51H34N6O23S6Na6 - Cancer Research - Angiogenesis - Zhang, Y.L., T.F. Keng, Y. Zhao, L. Wu, Z.Y. Zhang. - Suramin is an Active Site-Directed, Reversible, and Tight-Binding Inhibitor of Protein-Tyrosine Phosphatases. - Journal of Biological Chemistry. - Apoptosis and Clonogenic Cell Death in PC3 Human Prostrate Cancer Cells after Treatment with ? Radiation and Suramin. - Radiation Research. - Cadene, M., J. Duranton, A. North, M. Si-Tahar, M. Chignard, J.G. Bieth. - Inhibtion of Neutrophil Serine Proteinases by Suramin. - Journal of Biological Chemistry. - Waldhoer, M., E. Bofill-Cardona, G. Mulligan, M. Freissmuth, C. Nanoff. - Differential Uncoupling of A1 Adenosine and D2 Dopamine Receptors by Suramin and Didemethylated Suramin (NF037). - Molecular Pharmacology. - Gschwendt, M., W. Kittstein, F.J. Johannes. - Differential Effects of Suramin on Protein Kinase C Isoenzymes. A Novel Tool for Discriminating Protein Kinase C Activities. - FEBS Letters. |
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