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Geldanamycin.com is pleased to provide detailed technical information. Below are test methods and results detailing the quality of our products, as well as, safety measures for handling these products. For complete product descriptions and scientific references go to our Products page.
An extensive listing of web sites related to these products and their importance within scientific research is found on our Biolinks page. Thank you and we welcome the opportunity to aid you in your research.
Geldanamycin is a benzoquinone ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, and oncogenesis.
Product No: G-1047
Chemical Formula: C29H40N2O9
M.W.: 560.6
CAS No: [30562-34-6]
RTECS: LX8920000
Storage: 20°C, Toxic
Material Saftey Data Sheet
Certificate of Analysis
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Inhibits angiogenesis. Also acts a potent and cell permeable protein tyrosine kinase inhibitor.
Product No:H-1050
Chemical Formula: C30H42N2O9
M.W.: 574.66
CAS No: [70563-58-5]
Handling: Toxic, Hygroscopic
Storage: +4°C
Material Saftey Data Sheet
Certificate of Analysis
Ordering Information
17-AAG is an ansamycin antibiotic which binds to Hsp90 and alters it function. Hsp90 plays a key role in regulating the physiology of cells exposed to environmental stress and in maintaining the malignant phenotype of tumor cells.
Product No:A-1256
Chemical Formula: C31H42N2O9
M.W.: 574.86
CAS No: [75747-14-7]
RTECS: LX8920000
Handling: Toxic, Hygroscopic
Storage: +4°C
Material Saftey Data Sheet
Certificate of Analysis
Ordering Information
Radicicol, a macrocyclic antifungal antibitotic, has been shown to bind to a highly conserved pocket in the Hsp90 (heat shock protein 90) chaperone protein and inhibit the intrinsic ATPase activity of Hsp90.
Product No: R-1130
Chemical Formula: C18H17CIO6
M.W.: 364.78
CAS No: [12772-57-5]
Handling: Toxic, Hygroscopic
Storage: +4°C
Material Saftey Data Sheet
Certificate of Analysis
Ordering Information